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LAP

Catalog No.GC50358

Photocrosslinker for hydrogels

Products are for research use only. Not for human use. We do not sell to patients.

LAP Chemical Structure

Cas No.: 85073-19-4

Size Price Stock Qty
10mM (in 1mL DMSO)
$50.00
In stock
500mg
$9.00
In stock
1g
$15.00
In stock
5g
$54.00
In stock
10g
$95.00
In stock
25g
$207.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description of LAP

Photocrosslinker for hydrogels.

Fairbanks et al (2009) Photoinitiated polymerization of PEG-diacrylate with Li phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility. Biomaterials 30 6702 PMID:19783300 |Valkevich et al (2012) Forging isopeptide bonds using thiol-ene chemistry: site-specific coupling of ubiquitin molecules for studying the activity of isopeptidases J.Am.Chem.Soc. 134 6916 PMID:22497214

Chemical Properties of LAP

Cas No. 85073-19-4 SDF
Canonical SMILES CC1=C(C(P(C2=CC=CC=C2)(O[Li])=O)=O)C(C)=CC(C)=C1
Formula C16H16LiO3P M.Wt 294.21
Solubility DMSO : 25 mg/mL (84.97 mM; Need ultrasonic); H2O : 7.58 mg/mL (25.76 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of LAP

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.3989 mL 16.9947 mL 33.9893 mL
5 mM 0.6798 mL 3.3989 mL 6.7979 mL
10 mM 0.3399 mL 1.6995 mL 3.3989 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

In vivo Formulation Calculator (Clear solution) of LAP

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Reviews

Review for LAP

Average Rating: 5 ★★★★★ (Based on Reviews and 5 reference(s) in Google Scholar.)

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