LEI-301 is a potent inhibitor for the PLAAT family members with pIC50 values of 7.3, 6.6, 7.3 and 7.4 for PLAAT2, PLAAT3, PLAAT4 and PLAAT5, respectively. LEI-301 was selective over the proteins of the endocannabinoid system (ECS). Moreover, LEI-301 reduced the NAE levels, including anandamide, in cells overexpressing PLAAT2 or PLAAT5.
LEI-301
Catalog No.: GB40260Purity:>98.00%
LEI-301 is a potent inhibitor for the PLAAT family members with pIC50 values of 7.3, 6.6, 7.3 and 7.4 for PLAAT2, PLAAT3, PLAAT4 and PLAAT5, respectively. LEI-301 was selective over the proteins of the endocannabinoid system (ECS). Moreover, LEI-301 reduced the NAE levels, including anandamide, in cells overexpressing PLAAT2 or PLAAT5.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2571585-09-4
5mgQuote
$462.00
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $462.00 | Quote | -- |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
2571585-09-4
Molecular Formula
C25H25NO3
Molecular Weight
387.47
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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