Leonuriside A |
Catalog No.GC80411
One-Click Copy Product Info
|
Leonuriside A is a phenolic compound that can be isolated from Leonurus japonicus.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 121748-12-7
Sample solution is provided at 25 µL, 10mM.
_1-3.$$$39978408@51.jpg');)
_1-9.$$$38538795@65.jpg');)
_1-9.$$$39112701@51.jpg');)
_1-7.$$$37316672@70.jpg');)
_366-372.$$$36198801@70.jpg');)
.$$$38565142@65.jpg');)
_1867-1883.$$$33248023@67.jpg');)
_eads6055.$$$39977546@45.jpg');)
_eadm9805.$$$40080571@45.jpg');)
_eadj3020.$$$39666821@45.jpg');)
_1-20.$$$39757301@28.jpg');)
_1-24.$$$38898113@28.jpg');)
_273-287.$$$36806353@46.jpg');)
_1-16.$$$37156877@44.jpg');)
_1-19.$$$37460805@44.jpg');)
_1291-1307.$$$34518654@46.jpg');)
In Vitro, Leonuriside A (up to 50 μM; 30 min pretreatment, 24 h LPS incubation) inhibits nitric oxide production in LPS-stimulated RAW264.7 macrophages with an IC50 of 15.6 μM, with no significant cytotoxicity at concentrations up to 50 μM[2].
References:
[1]. Ba Vinh L, et al. Bioactive triterpene glycosides from the fruit of Stauntonia hexaphylla and insights into the molecular mechanism of its inflammatory effects. Bioorganic & medicinal chemistry letters. 2019 Aug 15;29(16):2085-2089.
[2]. Dang Hau Viet, et al. A New Megastigmane Glucoside and Other Constituents from Desmodium gangeticum, Journal of Chemistry, 2020, 7416973.
[3]. Minh TT. et al. Lignans from the stems of Clerodendrum inerme Gaertn. VJCH, 59: 187-191.
| Cas No. | 121748-12-7 | SDF | |
| Formula | C14H20O9 | M.Wt | 332.3 |
| Solubility | DMSO: 100 mg/mL (300.93 mM; Need ultrasonic) | Storage | Store at -20°C |
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.0093 mL | 15.0466 mL | 30.0933 mL |
| 5 mM | 601.9 μL | 3.0093 mL | 6.0187 mL |
| 10 mM | 300.9 μL | 1.5047 mL | 3.0093 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.50% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)