GLPBio

Lipid 29d

Catalog No.: GC92065Purity:>95.00%
COASDSData Sheet
Lipid 29d is an unsaturated ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.

Products are for research use only. Not for human use. We do not sell to patients.

Lipid 29d
Cas No.: 2921586-67-4
1 mgIn Stock
$105.00
1
5 mgIn Stock
$394.00
1
10 mgIn Stock
$578.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Lipid 29d is an unsaturated ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.1 Intravenous administration of LNPs containing lipid 29d and encapsulating mRNA encoding a luciferase reporter induce bioluminescence in the lungs and spleen of mice.

References:
[1]. Eygeris, Y., Gupta, M., Kim, J., et al.Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissuesProc. Natl. Acad. Sci. USA121(11)e2307813120(2024).

Product Documents

Purity:>95.00%Appearance:A solution in ethanol
COASDSData Sheet

Chemical Properties

CAS No.
2921586-67-4
Chemical Name
N-[3-(dimethylamino)propyl]-4,5,6,7-tetrahydro-6-[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-thieno[2,3-c]pyridine-3-carboxamide
SMILES
CCCCC/C=C\C/C=C\CCCCCCCC(N1CCC(C(C(NCCCN(C)C)=O)=C(NC(CCCCCCC/C=C\C/C=C\CCCCC)=O)S2)=C2C1)=O
Molecular Formula
C49H82N4O3S
Molecular Weight
807.3
Solubility
Ethanol: Sparingly Soluble: 1-10 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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