Prostaglandins

Limaprost is an analog of prostaglandin E1 (PGE1) with structural modifications intended to give it a prolonged half-life and greater potency.

5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4.

5-trans PGF2α tromethamine salt is a derivative of 5-trans PGF2α with increased water solubility.

Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids.

9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency.

Fluprostenol is a well-studied, potent analog of prostaglandin F2α (PGF2α) and acts primarily through the FP receptor.

A potential impurity found in commercial preparations of aceclofenac

A potential impurity in commercial preparations of aceclofenac

AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor.

AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor.

Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function.

Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells.

C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells.

Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype.

Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer.

The actions of many clinical prostaglandins, including those used for estrous synchronization and for reduction of intraocular pressure, are mediated through the FP receptor.

Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib.

Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2.

Dehydroevodiamine is an alkaloid that has been isolated from E.

Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat.

Diclofenac acyl-β-D-glucuronide allyl ester is an intermediate in the synthesis of the COX inhibitor metabolite diclofenac acyl-β-D-glucuronide .

Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac.

Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.

Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.