Home>>8-iso Prostaglandin A2-biotin

8-iso Prostaglandin A2-biotin (Synonyms: 8iso PGA2biotin)

Catalog No.GC42628

Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids.

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8-iso Prostaglandin A2-biotin Chemical Structure

Size Price Stock Qty
50μg
$82.00
In stock
100μg
$157.00
In stock
500μg
$658.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids. 8-iso Prostaglandin A2-biotin (8-iso PGA2-biotin) is an affinity probe which allows 8-iso PGA2 to be detected through an interaction with the biotin ligand. Biotinylated eicosanoids have been used to capture proteins which interact with the lipid.

Chemical Properties

Cas No. SDF
Synonyms 8iso PGA2biotin
Canonical SMILES O=C1C=C[C@H](/C=C/[C@@H](O)CCCCC)[C@@H]1C/C=C\CCCC(NCCCCCNC(CCCC[C@H]2SC[C@@](N3)([H])[C@]2([H])NC3=O)=O)=O
Formula C35H56N4O5S M.Wt 644.9
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.5506 mL 7.7531 mL 15.5063 mL
5 mM 0.3101 mL 1.5506 mL 3.1013 mL
10 mM 0.1551 mL 0.7753 mL 1.5506 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 10 reference(s) in Google Scholar.)

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