GLPBio

Livmoniplimab

Catalog No.: GC74573Purity:>99.00%Synonyms: ABBV-151; ARGX-115
COASDSData Sheet
Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1.

Products are for research use only. Not for human use. We do not sell to patients.

Livmoniplimab
Cas No.: 2412004-88-5
1 mgIn Stock
$279.00
1
5 mgIn Stock
$725.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors.

Livmoniplimab (250 μg; three times a week; 3 weeks; i.p.) exhibits anti-tumor activity in colon cancer mice[2].

References:
[1]. Tindall RR, et al. The TGF-β superfamily as potential therapeutic targets in pancreatic cancer. Front Oncol. 2024 Mar 4;14:1362247.
[2]. Guo J, et al. A novel GARP humanized mouse model for efficacy assessment of GARP-targeting therapies. Int Immunopharmacol. 2024 Mar 30;130:111782.

Product Documents

Purity:>99.00%Appearance:A liquid
COASDSData Sheet

Chemical Properties

CAS No.
2412004-88-5
Synonyms
ABBV-151; ARGX-115
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion

g/mol

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