GLPBio

LPA Receptor

LPA receptor belongs to GPCRs and is important for lipid signaling.

Products Related to LPA Receptor(12)

  • GC11374 structure
    GC11374Ki16425
    CAS: 355025-24-0
    Purity: >98.00%

    Ki16425 is an antagonist of the lysophosphatidic acid receptors LPA1 and LPA3 and Ki values are 0.25 and 0.36μM respectly. Ki16425 reduces the LPA-induced activation of p42/p44 MAPK.Blocks LPA-induced dephosphorylation of Yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (TAZ), inhibiting the Hippo signaling pathway.

  • GC14436 structure
    GC14436H2L5186303
    CAS: 139262-76-3
    Purity: >98.00%

    H2L5186303 is a selective lysophosphatidic acid receptor 2 (LPA₂; IC₅₀=9nM) antagonist.

  • GC15140 structure
    GC151401-Oleoyl lysophosphatidic acid sodium salt
    CAS: 325465-93-8
    Purity: >98.00%

    1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, as a potent bioactive phospholipid, is a LPA receptor activator.

  • GC15428 structure
    GC15428H2L 5765834
    CAS: 420841-84-5
    Purity: >99.00%

    lysophosphatidic acid receptors antagonist

  • GC15808 structure
    GC15808TC LPA5 4
    CAS: 1393814-38-4
    Purity: >98%

    TC LPA5 4 is a potent LPA5-selective receptor antagonist and a heparanase inhibitor with IC 50 values of 0.8μM and 10μM, respectively.

  • GC12362 structure
    GC12362ONO-7300243
    CAS: 638132-34-0
    Purity: >98.00%

    LPA1 antagonist

  • GC13476 structure
    GC13476AM966
    CAS: 1228690-19-4
    Purity: >98.50%

    A potent and selective LPA 1 receptor antagonist

  • GC15220 structure
    GC15220AM095
    CAS: 1345614-59-6
    Purity: >99.50%

    AM095 is a selective, orally bioavailable LPA1 antagonist with an IC 50 value of 0.73μM for mouse LPA1.

  • GC15908 structure
    GC15908AM-095 free base
    CAS: 1228690-36-5
    Purity: >99.00%

    A selective LPA 1 receptor antagonist

  • GC16558 structure
    GC16558DBIBB
    CAS: 1569309-92-7
    Purity: >98.00%

    LPA2 agonist

  • GC17617 structure
    GC17617Tetradecyl Phosphonate
    CAS: 4671-75-4
    Purity: >98%

    pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors

  • GC15062 structure
    GC15062Ki16198
    CAS: 355025-13-7
    Purity: >98.50%

    LPA antagonist