LT25 (compound 17) is a agonist of α5β1 integrin with EC 50 value of 9.9 nM [1].
References:
[1]. Monica Baiula, et al. New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins. J Med Chem. 2016 Nov 10;59(21):9721-9742.
References:
[1]. Monica Baiula, et al. New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins. J Med Chem. 2016 Nov 10;59(21):9721-9742.