GLPBio

Lubeluzole dihydrochloride

Catalog No.: GC72780Purity:>99.00%
COASDSData Sheet
Lubeluzole (didrochloride) is a neuroprotective agent which blockades neuronal voltage-gated sodium channels.

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Lubeluzole dihydrochloride
Cas No.: 144665-09-8
1 mgIn Stock
$126.00
1
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Citations

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

Description

Lubeluzole (didrochloride) is a neuroprotective agent which blockades neuronal voltage-gated sodium channels. Lubeluzole (didrochloride) also produces both tonic and block of cardiac sodium channels. Lubeluzole (didrochloride) is promising for research of antiarrthmic agents.

References:
[1]. Le Grand B, et al. Study of the interaction of lubeluzole with cardiac sodium channels. J Cardiovasc Pharmacol. 2003 Nov;42(5):581-7.
[2]. Le Grand B, et al. Lubeluzole-induced prolongation of cardiac action potential in rabbit Purkinje fibres. Fundam Clin Pharmacol. 2000 Mar-Apr;14(2):159-62.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
144665-09-8
Molecular Formula
C22H27Cl2F2N3O2S
Molecular Weight
506.44
Solubility
H2O : 2 mg/mL (3.95 mM; Need ultrasonic and warming)
Storage
-20°C, sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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