NKCC

NKCC (Na-K-Cl cotransporter) is an electrically silent membrane-bound channels that mediates Na and Cl reabsorption. It functions in regulating cell volume and ionic balance.

Products Related to NKCC(6)

GC12970 Furosemide
CAS: 54-31-9
Purity: >98.00%
GABAA receptors antagonist
GC15524 Bumetanide
CAS: 28395-03-1
Purity: >99.50%
NKCC cotransporter inhibitor
GC16795 DCA
CAS: 2156-56-1
Purity: >98.00%
DCA is a metabolic regulator in cancer cells' mitochondria with anticancer activity. DCA inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. DCA increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. DCA also works as NKCC inhibitor.
GC36091 Furosemide sodium
CAS: 41733-55-5
Purity: >99.50%
A loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter
GC38738 Azosemide
CAS: 27589-33-9
Purity: >97.00%
Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246??M and 0.197??M for hNKCC1A and NKCC1B, respectively.
GC79492 ML077
CAS: 1135304-61-8
Purity: >98%
ML007 is a selective antagonist targeting the neuron-specific potassium-chloride co-transporter 2 ( KCC2 ) with an IC 50 for KCC2 is 537 nM, while its inhibitory activity on KCC1 is extremely weak ( IC 50 > 50 μM).

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC12970	Furosemide	54-31-9	>98.00%
GC12970	GABAA receptors antagonist
GC15524	Bumetanide	28395-03-1	>99.50%
GC15524	NKCC cotransporter inhibitor
GC16795	DCA	2156-56-1	>98.00%
GC16795	DCA is a metabolic regulator in cancer cells' mitochondria with anticancer activity. DCA inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. DCA increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. DCA also works as NKCC inhibitor.
GC36091	Furosemide sodium	41733-55-5	>99.50%
GC36091	A loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter
GC38738	Azosemide	27589-33-9	>97.00%
GC38738	Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246??M and 0.197??M for hNKCC1A and NKCC1B, respectively.
GC79492	ML077	1135304-61-8	>98%
GC79492	ML007 is a selective antagonist targeting the neuron-specific potassium-chloride co-transporter 2 ( KCC2 ) with an IC 50 for KCC2 is 537 nM, while its inhibitory activity on KCC1 is extremely weak ( IC 50 > 50 μM).