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Home >> Signaling Pathways >> MAPK Signaling

MAPK Signaling

Targets for  MAPK Signaling

Products for  MAPK Signaling

  1. Cat.No. Product Name Information
  2. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol 2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol Chemical Structure
  3. GC60393 (-)-Zuonin A (-)-Zuonin A Chemical Structure
  4. GC13944 (5Z)-7-Oxozeaenol

    TAK1 mitogen-activated protein kinase kinase kinase (MAPKKK) inhibitor

     (5Z)-7-Oxozeaenol Chemical Structure
  5. GC34983 (E)-Necrosulfonamide (E)-Necrosulfonamide Chemical Structure
  6. GC63903 (E)-Osmundacetone (E)-Osmundacetone Chemical Structure
  7. GC62528 (Rac)-Hesperetin (Rac)-Hesperetin Chemical Structure
  8. GC41740 (S)-p38 MAPK Inhibitor III (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). (S)-p38 MAPK Inhibitor III Chemical Structure
  9. GC12851 10Z-Hymenialdisine Pan kinase inhibitor 10Z-Hymenialdisine Chemical Structure
  10. GC39325 2,5-Dihydroxyacetophenone 2,5-Dihydroxyacetophenone Chemical Structure
  11. GC63700 5,6,7-Trimethoxyflavone 5,6,7-Trimethoxyflavone Chemical Structure
  12. GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. 5-trans Prostaglandin E2 Chemical Structure
  13. GC12834 6-Bnz-cAMP sodium salt cAMP analog,PKA activator 6-Bnz-cAMP sodium salt Chemical Structure
  14. GC42616 7-oxo Staurosporine

    7-oxo Staurosporine is an antibiotic originally isolated from S.

     7-oxo Staurosporine Chemical Structure
  15. GC16929 8-Bromo-cAMP, sodium salt Cell-permeable cAMP analog that activates PKA 8-Bromo-cAMP, sodium salt Chemical Structure
  16. GC42622 8-bromo-Cyclic AMP 8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase. 8-bromo-Cyclic AMP Chemical Structure
  17. GC15352 8-CPT-Cyclic AMP (sodium salt) lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependent protein kinases, PKA and PKG 8-CPT-Cyclic AMP (sodium salt) Chemical Structure
  18. GC60037 A-3 hydrochloride A-3 hydrochloride Chemical Structure
  19. GA20623 Ac-muramyl-Ala-D-Glu-NH₂ Muramyl dipeptide (MDP) inhibits HIV replication in CD4? H9 lymphocytes.. Ac-muramyl-Ala-D-Glu-NH₂ Chemical Structure
  20. GC35242 Actein Actein Chemical Structure
  21. GC19019 Acumapimod Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 uM for p38α. Acumapimod Chemical Structure
  22. GC32797 AD80 AD80 Chemical Structure
  23. GC10204 AEG 3482 inhibitor of Jun kinase (JNK)-dependent apoptosis AEG 3482 Chemical Structure
  24. GC17265 AG-126 ERK1 (p44) and ERK2 (p42) inhibitor AG-126 Chemical Structure
  25. GC12646 AL 8697 p38α inhibitor,potent and selective AL 8697 Chemical Structure
  26. GC14899 AMG 548 P38α inhibitor,potent and selective AMG 548 Chemical Structure
  27. GC38518 AMG-548 dihydrochloride AMG-548 dihydrochloride Chemical Structure
  28. GC11559 Anisomycin

    JNK agonist, potent and specific

     Anisomycin Chemical Structure
  29. GC15240 APS-2-79 KSR-dependent MAPK modulator APS-2-79 Chemical Structure
  30. GC32692 APTO-253 (LOR-253) APTO-253 (LOR-253) Chemical Structure
  31. GN10063 Arctigenin Anti-inflammatory, antiproliferative Arctigenin Chemical Structure
  32. GC12882 AS 602801 Jun Kinase Inhibitor AS 602801 Chemical Structure
  33. GC10010 AS601245 A c-Jun NH2-terminal protein kinase inhibitor AS601245 Chemical Structure
  34. GC19041 ASK1-IN-1 ASK1-IN-1 is an apoptosis signal regulating kinase 1 (ASK1) inhibitor extracted from patent WO2016025474A1, Compound 4. ASK1-IN-1 Chemical Structure
  35. GC62426 ASK1-IN-2 ASK1-IN-2 Chemical Structure
  36. GN10494 Astragaloside IV Anti-inflammatory;extract of Astragali radix Astragaloside IV Chemical Structure
  37. GC17712 AT13148 Multi-AGC kinase inhibitor,ATP-competitive AT13148 Chemical Structure
  38. GC12297 AT7867

    Akt1/2/3 and p70S6K/PKA inhibitor

     AT7867 Chemical Structure
  39. GC10918 AT7867 dihydrochloride Akt1 and p70S6K/PKA inhibitor AT7867 dihydrochloride Chemical Structure
  40. GC31667 AX-15836 AX-15836 Chemical Structure
  41. GC15055 AZ 628

    Raf kinases,potent and ATP-competitive

     AZ 628 Chemical Structure
  42. GC19479 AZ304

    A dual inhibitor

     AZ304 Chemical Structure
  43. GC19048 AZD-0364 AZD-0364 is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1, compound example 18, has an IC50 of 0.6 nM. AZD-0364 Chemical Structure
  44. GC17030 AZD6244(Selumetinib) A MEK inhibitor AZD6244(Selumetinib) Chemical Structure
  45. GC31924 AZD7624 AZD7624 Chemical Structure
  46. GC14643 AZD8330 MEK 1/2 inhibitor AZD8330 Chemical Structure
  47. GC38738 Azosemide Azosemide Chemical Structure
  48. GC10534 B-Raf IN 1 B-Raf inhibitor B-Raf IN 1 Chemical Structure
  49. GC12151 B-Raf inhibitor A B-Raf inhibitor B-Raf inhibitor Chemical Structure
  50. GC11599 B-Raf inhibitor 1 Potent and selective B-Raf inhibitor B-Raf inhibitor 1 Chemical Structure
  51. GC14907 B-Raf inhibitor 1 dihydrochloride B-Raf inhibitor,potent and selective B-Raf inhibitor 1 dihydrochloride Chemical Structure
  52. GN10590 Bakuchiol Extracted from Psoralea corylifolia L. fruit;Store the product in sealed, cool and dry condition Bakuchiol Chemical Structure
  53. GC33305 Balamapimod (MKI 833) Balamapimod (MKI 833) Chemical Structure
  54. GC34342 BAY885 BAY885 Chemical Structure
  55. GC32950 Belvarafenib Belvarafenib Chemical Structure
  56. GC35488 Belvarafenib TFA Belvarafenib TFA Chemical Structure
  57. GC19066 BGB-283 BGB-283 is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. BGB-283 Chemical Structure
  58. GC12904 BI 78D3 Competitive JNK inhibitor BI 78D3 Chemical Structure
  59. GC17828 BI-847325 dual inhibitor of MEK and Aurora kinases BI-847325 Chemical Structure
  60. GC18178 BI-882370 BI-882370 Chemical Structure
  61. GC13468 BI-D1870 P90 RSK inhibitor,ATP-competitive and cell-permeable BI-D1870 Chemical Structure
  62. GC11497 BIRB 796 (Doramapimod) P38 MAPK inhibitor,cell permeable and highly selective BIRB 796 (Doramapimod) Chemical Structure
  63. GC35525 Bisabolangelone Bisabolangelone Chemical Structure
  64. GC15693 BIX 02188 MEK5 inhibitor,potent and selective BIX 02188 Chemical Structure
  65. GC12220 BIX 02189 Selective MEK5 inhibitor BIX 02189 Chemical Structure
  66. GC12982 BIX 02565 RSK2 inhibitor BIX 02565 Chemical Structure
  67. GC16997 BMS-582949 p38 MAPK inhibitor BMS-582949 Chemical Structure
  68. GC10593 BMS-582949 hydrochloride p38 MAPK inhibitor BMS-582949 hydrochloride Chemical Structure
  69. GC42968 BPIQ-II (hydrochloride) BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM). BPIQ-II (hydrochloride) Chemical Structure
  70. GC12482 BRAF inhibitor Potent B-raf inhibitor BRAF inhibitor Chemical Structure
  71. GC16779 BRD 7389 P90 RSK inhibitor BRD 7389 Chemical Structure
  72. GC35565 Bucladesine calcium salt A membrane permeable selective activator of PKA Bucladesine calcium salt Chemical Structure
  73. GC15524 Bumetanide NKCC cotransporter inhibitor Bumetanide Chemical Structure
  74. GC11605 C-1 protein kinase C inhibitor C-1 Chemical Structure
  75. GC10693 c-JUN peptide JNK/c-Jun interaction inhibitor c-JUN peptide Chemical Structure
  76. GC43065 C2 Phytoceramide (t18:0/2:0) C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells. C2 Phytoceramide (t18:0/2:0) Chemical Structure
  77. GC40352 Cafestol Cafestol is a natural diterpene which is abundant in unfiltered coffee. Cafestol Chemical Structure
  78. GC10941 cAMPS-Rp, triethylammonium salt Cell-permeable cAMP analog, competitive antagonist of cAMP-induced activation of PKA cAMPS-Rp, triethylammonium salt Chemical Structure
  79. GC12706 cAMPS-Sp, triethylammonium salt Cell-permeable cAMP analog that activates cAMP receptor protein PKA cAMPS-Sp, triethylammonium salt Chemical Structure
  80. GN10016 Carnosol Extracted from Labiatae rosemary;Store the product in sealed, cool and dry condition Carnosol Chemical Structure
  81. GC43167 CAY10561 The extracellular signal-regulated kinase (ERK) signal transduction pathway regulates a diverse array of cellular processes. CAY10561 Chemical Structure
  82. GC40650 CAY10706 CAY10706 is a ligustrazine-curcumin hybrid that promotes intracellular reactive oxygen species accumulation preferentially in lung cancer cells. CAY10706 Chemical Structure
  83. GC43198 CAY10717 CAY10717 is a multi-targeted kinase inhibitor that exhibits greater than 40% inhibition of 34 of 104 kinases in an enzymatic assay at a concentration of 100 nM. CAY10717 Chemical Structure
  84. GC50400 CC 401 dihydrochloride High affinity JNK inhibitor; also inhibits HCMV replication CC 401 dihydrochloride Chemical Structure
  85. GC13529 CC-401 JNK inhibitor,ATP-competitive CC-401 Chemical Structure
  86. GC14197 CC-401 hydrochloride A JNK inhibitor CC-401 hydrochloride Chemical Structure
  87. GC62492 CC-90001 CC-90001 Chemical Structure
  88. GC32900 CC-90003 CC-90003 Chemical Structure
  89. GC10446 CC-930 JNK inhibitor,potent and selective CC-930 Chemical Structure
  90. GC63441 CC-99677 CC-99677 Chemical Structure
  91. GC19090 CCG215022 CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 uM, 0.38±0.06 uM and 3.9±1 uM for GRK2, GRK5 and GRK1, respectively. CCG215022 Chemical Structure
  92. GC19091 CCT196969 CCT196969, a pan-Raf inhibitor, inhibits B-Raf with an IC50 of 0.1 uM. CCT196969 Chemical Structure
  93. GC40054 CCT241161 CCT241161 is a multi-kinase inhibitor that inhibits B-RAF, B-RAFV600E, C-RAF, Src, and LCK (IC50s = 252, 15, 6, 15, and 3 nM, respectively). CCT241161 Chemical Structure
  94. GC61865 Cearoin Cearoin Chemical Structure
  95. GC12841 CEP 1347 JNK inhibitor CEP 1347 Chemical Structure
  96. GC16845 CEP-32496 BRAF(V600E)inhibitor,highly potent CEP-32496 Chemical Structure
  97. GC17860 CEP-32496 hydrochloride B-Raf/C-Raf inhibitor,highly potent CEP-32496 hydrochloride Chemical Structure
  98. GC15391 Cercosporamide Mnk2 and JAK3 inhibitor Cercosporamide Chemical Structure
  99. GC15525 cGMP Dependent Kinase Inhibitor Peptide cGMP-dependent protein kinase (PKG) inhibitor cGMP Dependent Kinase Inhibitor Peptide Chemical Structure
  100. GC10666 CGP 57380 MNK1 inhibitor, specific and selective CGP 57380 Chemical Structure
  101. GC12532 CHPG mGlu5 metabotropic glutamate receptor agonist CHPG Chemical Structure

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