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MB 0223

Catalog No.GC50574

Dynamin-related GTPase DRP1 partial inhibitor

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MB 0223 Chemical Structure

Cas No.: 2247732-89-2

Size Price Stock Qty
10 mg
$322.00
In stock
50 mg
$1,360.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fusion.

Mallat et al (2018) Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1. Biochem.Biophys.Res.Commun. 499 556 PMID:29601815

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Average Rating: 5 ★★★★★ (Based on Reviews and 14 reference(s) in Google Scholar.)

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