GLPBio

MRT 10

Catalog No.: GC12192Purity:>98.00%
MRT 10 is a seven-transmembrane receptor smoothened (Smo) antagonist with an IC50 of 0.65 μM in the micromolar range in various Hedgehog (Hh) assays. MRT 10 binds to the Smo receptor at the level of the Bodipycyclopamine binding site. MRT 10 can be used for the research of cancer.

Products are for research use only. Not for human use. We do not sell to patients.


MRT 10
Cas No.: 330829-30-6
1mgIn Stock
$52.00
1
5mgIn Stock
$154.00
1
10mgIn Stock
$256.00
1
25mgIn Stock
$571.00
1
50mgIn Stock
$309.00
1
100mgIn Stock
$443.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
330829-30-6
Chemical Name
N-((3-benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide
SMILES
S=C(NC(C1=CC(OC)=C(C(OC)=C1)OC)=O)NC2=CC=CC(NC(C3=CC=CC=C3)=O)=C2
Molecular Formula
C24H23N3O5S
Molecular Weight
465.52
Solubility
DMF: 33 mg/ml,DMSO: 33 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.3 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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