MTH1

MTH1 (human MutT homolog 1) is an antimutagenic purine nucleoside triphosphatase that sanitize oxidized nucleotide pools. It protects the cell from oxidative stress-induced cell dysfunction or death. It is a target for anticancer treatment.

Products Related to MTH1(4)

GC13136 (S)-Crizotinib
CAS: 1374356-45-2
Purity: >99.50%
Potent MTH1 inhibitor
GC12716 TH588
CAS: 1609960-31-7
Purity: >98.50%
TH588 is an inhibitor of MTH1 (NUDT1; IC 50 =5nM).
GC17601 TH287
CAS: 1609960-30-6
Purity: >98.00%
MTH1 inhibitor
GC17613 SCH 51344
CAS: 171927-40-5
Purity: >98%
SCH 51344 inhibits Ras induced malignant transformation and prevents anchorage-independent growth of oncogene transformed fibroblasts.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC13136	(S)-Crizotinib	1374356-45-2	>99.50%
GC13136	Potent MTH1 inhibitor
GC12716	TH588	1609960-31-7	>98.50%
GC12716	TH588 is an inhibitor of MTH1 (NUDT1; IC 50 =5nM).
GC17601	TH287	1609960-30-6	>98.00%
GC17601	MTH1 inhibitor
GC17613	SCH 51344	171927-40-5	>98%
GC17613	SCH 51344 inhibits Ras induced malignant transformation and prevents anchorage-independent growth of oncogene transformed fibroblasts.