mUNO is a tumor-homing peptide (mUNO, sequence: "CSPGAK") that specifically binds to mouse CD206, targeting tumor-associated macrophages that express CD206/MRC1. mUNO can interact with human recombinant CD206 [1].
In Vitro, FAM-mUNO (3 nM; 45 min) selectively binds to IL-4-differentiated CD206+ human monocyte-derived macrophages in vitro[1].
References:
[1]. Eliana K Asciutto, et al. Phage-Display-Derived Peptide Binds to Human CD206 and Modeling Reveals a New Binding Site on the Receptor. J Phys Chem B. 2019 Mar 7;123(9):1973-1982.
In Vitro, FAM-mUNO (3 nM; 45 min) selectively binds to IL-4-differentiated CD206+ human monocyte-derived macrophages in vitro[1].
References:
[1]. Eliana K Asciutto, et al. Phage-Display-Derived Peptide Binds to Human CD206 and Modeling Reveals a New Binding Site on the Receptor. J Phys Chem B. 2019 Mar 7;123(9):1973-1982.