GLPBio

Nisotirostide

Catalog No.: GC74302Purity:>99.00%Synonyms: LY-3457263
Nisotirotide (LY-3457263) is a PYY analog agonist studied in type 2 diabetes and obesity.

Products are for research use only. Not for human use. We do not sell to patients.


Nisotirostide
Cas No.: 2663844-45-7
1 mgIn Stock
$90.00
1
5 mgIn Stock
$225.00
1
10 mgIn Stock
$360.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Nisotirotide (LY-3457263) is a PYY analog agonist studied in type 2 diabetes and obesity.

References:
[1]. Kloock S, et al. Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery Pharmacol Ther. 2023 Nov;251:108549.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
2663844-45-7
Synonyms
LY-3457263
Molecular Formula
C230H343N59O65
Molecular Weight
4974.53
Solubility
DMSO : 125 mg/mL (25.13 mM; Need ultrasonic)
Storage
Sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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