GLPBio

NLRP3 modulator 7 TFA

Catalog No.: GC79414Purity:>98.00%
COASDSData Sheet
NLRP3 modulator 7 (Compound 17B) TFA is a NLRP3 inflammasome modulator.

Products are for research use only. Not for human use. We do not sell to patients.

NLRP3 modulator 7 TFA
1mgIn Stock
$259.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

NLRP3 modulator 7 (Compound 17B) TFA is a NLRP3 inflammasome modulator. NLRP3 modulator 7 TFA inhibits LPS -induced IL-1β release in fresh human whole blood. NLRP3 modulator 7 TFA can be used in studies related to NLRP3 inflammasome activation and innate immune signaling [1].

In Vitro, NLRP3 modulator 7 (Compound 17B) TFA inhibits IL-1β production in immune cells stimulated via NLRP3 inflammasome activation with an IC50 < 500 nM[1].

References:
[1]. Collins J, et al. NLRP3 modulators. WO 2023/178099 A1. World Intellectual Property Organization. 2023-09-21.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Molecular Formula
C21H23F6N3O4
Molecular Weight
495.42
Storage
Store at -20°C, sealed storage, away from moisture and light
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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