GLPBio

Pentapeptide-3 (acetate)

Catalog No.: GC49689Purity:>95.00%Synonyms: H-GPRPA-NH2, H-Gly-Pro-Arg-Pro-Ala-NH2
COASDSData Sheet
A cosmeceutical peptide

Products are for research use only. Not for human use. We do not sell to patients.

Pentapeptide-3 (acetate)
Cas No.: N/A
250 mgIn Stock
$111.00
1
500 mgIn Stock
$213.00
1
1 gIn Stock
$404.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Pentapeptide-3 is a cosmeceutical peptide and pentapeptide fragment of the temple viper (T. wagleri) venom peptide Waglerin-1.1 It is an antagonist of nicotinic acetylcholine receptors (nAChRs).2

1.Schagen, S.K.Topical peptide treatments with effective anti-aging resultsCosmetics4(2)(2017) 2.Zhmak, M.N., Utkin, Y.N., Andreeva, T.V., et al.Peptide inhibitors of nicotinic acetylcholine receptorUS 9,550,808 B2(2017)

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
N/A
Synonyms
H-GPRPA-NH2, H-Gly-Pro-Arg-Pro-Ala-NH2
SMILES
O=C([C@H]1N(CCC1)C(CN)=O)N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N)=O)=O)=O.OC(C)=O
Molecular Formula
C21H37N9O5 • XC2H4O2
Molecular Weight
495.6
Solubility
DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: insol,PBS (pH 7.2): 5 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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