GLPBio

PG 34

Catalog No.: GC71020Purity:>98.00%
COASDSData Sheet
PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC50=68 μM), and a close structural analog of OSMI-1 .

Products are for research use only. Not for human use. We do not sell to patients.

PG 34
Cas No.: 1681056-62-1
5 mgIn Stock
$135.00
1
10 mgIn Stock
$225.00
1
25 mgIn Stock
$495.00
1
50 mgIn Stock
$855.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC50=68 μM), and a close structural analog of OSMI-1 .

PG34 (0.5-50 µM; 24 h) shows no detectable inhibition of OGT in CHO cells, displays no effect on apoptotic signaling, and shows a moderate effect on cell viability only at the highest concentration[1].

References:
[1]. Rodrigo F Ortiz-Meoz, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10(6):1392-7.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1681056-62-1
Molecular Formula
C28H25N3O5S2
Molecular Weight
547.65
Solubility
DMSO : 100 mg/mL (182.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
4°C, sealed storage, away from moisture and light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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