GLPBio

Phytantriol

Catalog No.: GC91939Purity:>95.00%
Phytantriol is an aliphatic alcohol that has been used in the formation of liquid crystalline nanoparticles (LCNPs) and cubosomes.

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Phytantriol
Cas No.: 74563-64-7
100 mgIn Stock
$69.00
1
250 mgIn Stock
$154.00
1
500 mgIn Stock
$275.00
1
1 gIn Stock
$412.00
1

Citations

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

Phytantriol is an aliphatic alcohol that has been used in the formation of liquid crystalline nanoparticles (LCNPs) and cubosomes.1,2 Cubosomes containing phytantriol are bactericidal against LPS-deficient and polymyxin-resistant A. baumannii strains.1 LCNPs containing phytantriol and encapsulating the isoquinoline alkaloid berberine reduce TNF-α and inducible nitric oxide synthase (iNOS) levels and the production of reactive oxygen species (ROS) in LPS-activated RAW 264.7 macrophages.2

References:
[1]. Lai, X., Ding, Y., Wu, C.M., et al.Phytantriol-based cubosome formulation as an antimicrobial against lipopolysaccharide-deficient Gram-negative bacteriaACS Appl. Mater. Interfaces12(40)44485-44498(2020).
[2]. Alnuqaydan, A.M., Almutary, A.G., Azam, M., et al.Phytantriol-based berberine-loaded liquid crystalline nanoparticles attenuate inflammation and oxidative stress in lipopolysaccharide-induced RAW26.
[4]. 7 macrophagesNanomaterials (Basel)12(23)4312(2022).

Product Documents

Purity:>95.00%Appearance:An oil

Chemical Properties

CAS No.
74563-64-7
Chemical Name
3,7,11,15-tetramethyl-1,2,3-hexadecanetriol
SMILES
OCC(C(C)(CCCC(CCCC(CCCC(C)C)C)C)O)O
Molecular Formula
C20H42O3
Molecular Weight
330.6
Solubility
DMSO: Soluble: ≥10 mg/ml,Ethanol: Soluble: ≥10 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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