GLPBio

PI3Kδ-IN-15

Catalog No.: GC72806Purity:>99.00%
COASDSData Sheet
PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC50 of 0.5 nM for p110δ.

Products are for research use only. Not for human use. We do not sell to patients.

PI3Kδ-IN-15
Cas No.: 870281-17-7
5 mgIn Stock
$212.00
1
10 mgIn Stock
$338.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC50 of 0.5 nM for p110δ. PI3Kδ-IN-15 inhibits PI3Kδ with >30-fold higher potency than PI3Kγ, PI3Kβ, and PI3Kα[1].


References:
[1]. Yeon Su Kim, et al. Synthesis and biological evaluation of novel purinyl quinazolinone derivatives as PI3Kδ-specific inhibitors for the treatment of hematologic malignancies. Bioorg Med Chem. 2021 Sep 1;45:116312.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
870281-17-7
Molecular Formula
C21H16FN7O
Molecular Weight
401.4
Solubility
DMSO : 100 mg/mL (249.13 mM; ultrasonic and warming and heat to 60°C)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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