CD Antigens

Ubamatamab (REGN4018) is a humanized bispecific antibody targeted against Mucin 16 (MUC16) and CD3.

Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors.

Solitomab (AMG 110) is a bispecific anti-CD3 and anti-epithelial-cell-adhesion-molecule (EpCAM) antibody.

Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II.

Fianlimab (REGN3767) is a human monoclonal antibody that targets the immune checkpoint receptor LAG-3 on T cells and has anti-tumour activity.

Flotetuzumab (MGD006; S80880) is an investigational CD123/CD3 bispecific dual-affinity retargeting antibody (DART) molecule.

Ligufalimab (AK 117) is a humanized IgG4 anti-CD47 monoclonal antibody.

Mezagitamab (TAK-079) is a IgG1λ anti-CD38 monoclonal antibody.

Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells.

Nivatrotamab (Hu3F8-BsAb) is a humanized anti-GD2/CD3 bispecific antibody.

Obexelimab (XmAb5871) is a humanized anti-CD19 antibody.

Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody.

Plamotamab (XmAb-13676) is a human bispecific antibody (bsAb) that binds CD3 and CD20.

Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1.

Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E.

Pasotuxizumab (BAY 2010112) is a PSMA and CD3 bispecific T-cell engager (BiTE).

Linvoseltamab is a bispecific antibody targeting to both BCMA (TNFRSF17) and CD3 epsilon.

Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells.

Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II.

Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3).

LY3541860 is a selective anti- CD19 antibody that both binds human CD19 with high affinity and selectively binds human B cells ( K d values: 76.8 pM and 94.5 nM for humans and cynomolgus monkeys, respectively).

Anti-CD19 Antibody (FMC63) is an antibody that binds to CD19, with a human K d value ranging from 0.42 nM to 149 nM.

Zeclantamig is an immunoglobuline (H-gamma1_L-kappa)_scFvhk-G1(h-CH2-CH3), anti-[ Homo sapiens EPCAM et anti-[ Homo sapiens CD3E ], anticorps monoclonal chimérique, bispécifique, trivalent [1] .

CD38-IN-6 is an orally active CD38 inhibitor.