Pyk2
Pyk2 is a nonreceptor cytoplasmic protein tyrosine kinase. It is involved in Ca(2+)-induced regulation of ion channel and MAP kinase activation. It plays a role in various cellular events such as cell motility, cell polarization, adhesion, reorganization of actin cytoskeleton etc.
Products Related to Pyk2(8)
- GC10810PF-562271 HClCAS: 939791-41-0Purity: >98%
PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively.
- GC14767PF-00562271CAS: 939791-38-5Purity: >99.00%
PF-562271 (VS-6062) besylate is a potent ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase, with an IC50 of 1.5 nM and 13 nM, respectively.
- GC16821TAE226(NVP-TAE226)CAS: 761437-28-9Purity: >98.00%
TAE226(NVP-TAE226) is a potent ATP-competitive inhibitor that inhibits a variety of tyrosine protein kinases, especially FAK and IGF-IR kinases, with IC 50 values of 5.5nM and 140nM, respectively.
- GC61852PF-4618433CAS: 1166393-85-6Purity: >98.00%
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM.
- GC73424PRT062607 acetateCAS: 1370261-98-5Purity: >99.00%
PRT062607 (P505-15) acetate is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induction Apoptosis.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10810 | PF-562271 HCl | 939791-41-0 | >98% | |
PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively. | ||||
| GC14407 | PF-431396 | 717906-29-1 | >98.50% | |
Pyk2 and FAK inhibitor | ||||
| GC15380 | PF-562271 | 717907-75-0 | >98.00% | |
PF-562271 is a potent small-molecule inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) with a IC 50 of 1.5 and 14nmol/L, respectively. | ||||
| GC14767 | PF-00562271 | 939791-38-5 | >99.00% | |
PF-562271 (VS-6062) besylate is a potent ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase, with an IC50 of 1.5 nM and 13 nM, respectively. | ||||
| GC16821 | TAE226(NVP-TAE226) | 761437-28-9 | >98.00% | |
TAE226(NVP-TAE226) is a potent ATP-competitive inhibitor that inhibits a variety of tyrosine protein kinases, especially FAK and IGF-IR kinases, with IC 50 values of 5.5nM and 140nM, respectively. | ||||
| GC61852 | PF-4618433 | 1166393-85-6 | >98.00% | |
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. | ||||
| GC73424 | PRT062607 acetate | 1370261-98-5 | >99.00% | |
PRT062607 (P505-15) acetate is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induction Apoptosis. | ||||
| GC74116 | Pyk2-IN-2 | 1271418-15-5 | >98.00% | |
Pyk2-IN-2 (compound 13j) is an inhibitor of Pyk2 with an IC50 of FAK kinase of 0.608 μM. | ||||