Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 µg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 µg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
Quinaldopeptin
Catalog No.: GC44798Purity:>95.00%
Quinaldopeptin is a quinomycin antibiotic.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130743-07-6
500μgIn Stock
$615.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 500μg | $615.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>95.00%Appearance:A Powder
Chemical Properties
CAS No.
130743-07-6
SMILES
O=C(CN(C)C(CNC([C@@]1([H])N(C([C@@](NC(C2=NC(C=CC=C3)=C3C=C2O)=O)([H])[C@H](C)NC([C@@]4([H])N5CCCC4)=O)=O)CCCC1)=O)=O)N(CCCC6)[C@]6([H])C(N[C@@H](C)[C@](NC(C7=NC(C=CC=C8)=C8C=C7O)=O)([H])C(N9CCCC[C@@]9([H])C(NCC(N(C)CC5=O)=O)=O)=O)=O
Molecular Formula
C62H78N14O14
Molecular Weight
1243.4
Solubility
DMF: soluble,DMSO: soluble,Ethanol: slightly soluble,Methanol: slightly soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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