Quinine is an alkaloid antimalarial agent that has MIC values ranging from 10 to 500 nM for 60 Thai isolates of P. falciparum. It inhibits hemozoin formation in purified trophozoites, leading to an increase in free heme, similar to the mechanism of action of chloroquine . In mice, quinine reduces P. berghei parasite load in the blood with a minimum effective dose (MED) of 150 mg/kg. Formulations containing quinine have been used in the treatment of uncomplicated malaria.
Quinine
Catalog No.: GC41455Purity:>99.50%Synonyms: NSC 192949
Quinine is an alkaloid antimalarial agent that has MIC values ranging from 10 to 500 nM for 60 Thai isolates of P.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130-95-0
500mgIn Stock
$28.00
1
1gIn Stock
$35.00
1
5gIn Stock
$56.00
1
10gIn Stock
$78.00
1
25gIn Stock
$112.00
1
50gIn Stock
$146.00
1
100gIn Stock
$189.00
1
500gIn Stock
$322.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 500mg | $28.00 | In Stock | 1 | |
| 1g | $35.00 | In Stock | 1 | |
| 5g | $56.00 | In Stock | 1 | |
| 10g | $78.00 | In Stock | 1 | |
| 25g | $112.00 | In Stock | 1 | |
| 50g | $146.00 | In Stock | 1 | |
| 100g | $189.00 | In Stock | 1 | |
| 500g | $322.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.50%Appearance:A solid
Chemical Properties
CAS No.
130-95-0
Synonyms
NSC 192949
SMILES
COC1=CC=C2C(C([C@@H](O)[C@]3([H])C[C@H]4[C@@H](C=C)C[N@@]3CC4)=CC=N2)=C1
Molecular Formula
C20H24N2O2
Molecular Weight
324.4
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
Storage
4°C, protect from light, stored under nitrogen
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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