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(rac)-BDM88951

Catalog No.GC79563 Copy One-Click Copy Product Info

(rac)-BDM88951 is the racemate of BDM88951.

Products are for research use only. Not for human use. We do not sell to patients.

(rac)-BDM88951 Chemical Structure

Size Price Stock Qty
10mM (in 1mL DMSO)
$354.00
In stock
1mg
$126.00
In stock
5mg
$313.00
In stock
10mg
$520.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of (rac)-BDM88951

(rac)-BDM88951 is the racemate of BDM88951. BDM88951 (Compound 4 d) is a selective ERAP2 inhibitor with an IC50 of 19 nM. BDM88951 significantly inhibits antigen presentation in HEK cells. BDM88951 can be used for research on autoimmune diseases and cancer [1].

References:
[1]. Camberlein V, et al. Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis. Angew Chem Int Ed Engl. 2022 Sep 26;61(39):e202203560.

Chemical Properties of (rac)-BDM88951

Cas No. SDF
Formula C23H23N5O5S2 M.Wt 513.59
Solubility DMSO: 100 mg/mL (194.71 mM; Need ultrasonic) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (rac)-BDM88951

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.9471 mL 9.7354 mL 19.4708 mL
5 mM 389.4 μL 1.9471 mL 3.8942 mL
10 mM 194.7 μL 973.5 μL 1.9471 mL
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In vivo Formulation Calculator (Clear solution) of (rac)-BDM88951

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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