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Ractopamine-d 6 (Synonyms: LY031537 free base-d6)

Catalog No.GC81704 Copy One-Click Copy Product Info

Ractopamine -d 6 is the deuterium labeled Ractopamine.

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Ractopamine-d 6 Chemical Structure

Cas No.: 1185177-97-2

Size Price Stock Qty
1mg
$562.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of Ractopamine-d 6

Ractopamine -d 6 is the deuterium labeled Ractopamine. Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K d values of ~25 nM for pig β 1 AR and β 2 AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs [1] [2] [3].

In Vitro, Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

References:
[1]. Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91(9):4180-4187.
[2]. Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120(12):1677-1683.
[3]. S. E. Mills, Biological basis of the ractopamine response, Journal of Animal Science, Volume 80, Issue E-suppl_2, 2002, Pages E28-E32.

Chemical Properties of Ractopamine-d 6

Cas No. 1185177-97-2 SDF
Synonyms LY031537 free base-d6
Formula C18H17D6NO3 M.Wt 307.42
Solubility Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Ractopamine-d 6

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1 mg 5 mg 10 mg
1 mM 3.2529 mL 16.2644 mL 32.5288 mL
5 mM 650.6 μL 3.2529 mL 6.5058 mL
10 mM 325.3 μL 1.6264 mL 3.2529 mL
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In vivo Formulation Calculator (Clear solution) of Ractopamine-d 6

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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