Antiparasitics

Anacardic acid diene is a polyunsaturated form of anacardic acid that has been found in cashew nut shell liquid.

2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 μM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 μM.

Cardol diene is a phenol found in cashew nut shell liquid.

Cardol triene is a phenol found in cashew nut shell liquid that competitively and irreversibly inhibits mushroom tyrosinase (IC50 = 22.5 μM).

Penicolinate A is a fungal metabolite produced by Penicillium sp.

Methylcardol triene is a phenol found in cashew nut shell liquid that inhibits α-glucosidase (IC50 = 39.6 μM).

(R)-(-)-Mellein is an antibiotic isolated from culture fluids of this Aspergillus.

Asterriquinol D dimethyl ether is a fungal metabolite that has been found in A.

19,20-Epoxycytochalasin C is a fungal metabolite originally isolated from Nemania sp.

19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp.

5-hydroxy Thiabendazole (5-OH TBZ) is a major metabolite of the anthelmintic thiabendazole.

Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a.

Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a.

Cambendazol is one of the most effective agents for the therapy of human strongyloidiasis and .

Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin.

DDD85646 is a potent inhibitor of Trypanosoma brucei N-myristoyltransferase (NMT), exhibiting half-maximal inhibitory concentration (IC₅₀) values of 2nM against T. brucei NMT (TbNMT) and 4nM against human NMT (hNMT).

Deethylindanomycin is a polyether antibiotic that has been found in S.

Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities.

Doramectin aglycone is an acid degradation product of doramectin, a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide.

Doramectin monosaccharide is an acid degradation product of doramectin, a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes.

Drimentine A is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.

Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.

Febrifugine is a quinazolinone alkaloid originally isolated from D.

FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P.