GLPBio

CGRP

CGRP (calcitonin gene related peptide) is a potent peptide vasodilator and can function in the transmission of pain.

Products Related to CGRP (40)

  • GC66408 structure
    GC66408Fremanezumab
    CAS: 1655501-53-3
    Purity: >95.00%

    Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab has the potential for chronic migraine research.

  • GC68821 structure
    GC68821Cagrilintide acetate
    Purity: >99.00%

    Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylin analogue. Cagrilintide acetate causes dose-dependent reduction in food intake and significant weight loss. It can be used for research on obesity.

  • GC69077 structure
    GC69077Eptinezumab
    CAS: 1644539-04-7
    Purity: >99.00%

    Eptinezumab is a human monoclonal antibody that binds to calcitonin gene-related peptide (CGRP) and blocks its binding to receptors. Eptinezumab can be used for the prevention of migraine headaches in adults.

  • GC69081 structure
    GC69081Erenumab
    CAS: 1582205-90-0
    Purity: >97.00%

    Erenumab is a fully human monoclonal antibody that inhibits the calcitonin gene-related peptide (CGRP) receptor. It can be used for preventing episodic migraines.

  • GC72093 structure
    GC72093α-CGRP (mouse, rat) (TFA)
    Purity: >99.00%

    α-CGRP (mouse, rat) TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator.

  • GC72110 structure
    GC72110α-CGRP(human) TFA
    Purity: >98.00%

    α-CGRP(human) TFA is a regulatory neuropeptide of 37 amino acids.

  • GC72190 structure
    GC72190Cagrilintide
    CAS: 1415456-99-3
    Purity: >98.00%

    Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist.

  • GC72813 structure
    GC72813(3R,5R,6S)-Atogepant
    Purity: >99.00%

    (3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of Atogepant.

  • GC74300 structure
    GC74300β-CGRP (mouse)
    Purity: >99.50%

    β-CGRP (mouse) is a calcitonin gene-related peptide that induces vasodilation.

  • GC79274 structure
    GC79274CTR/AMYR modulator-2
    CAS: 3108095-52-6
    Purity: >98.00%

    CTR/AMYR modulator-2 is a dual agonist of human amylin receptor 3 ( AMY3R ) and calcitonin receptor ( CTR ).

  • GC79275 structure
    GC79275KBP-089
    CAS: 1776112-67-4
    Purity: >99.00%

    KBP-089 is a dual Amylin and Calcitonin Receptor agonist.

  • GC79279 structure
    GC79279CLR/RAMP3-receptor antagonist-1
    CAS: 2252341-45-8
    Purity: >98%

    CLR/RAMP3-receptor antagonist-1 is a selective antagonist of the CLR/RAMP3 receptor ( CLR/RAMP3, AM 2 receptor ), with pIC 50 values of 5.86, 9.21 and 9.07 against AM 1 (CLR/RAMP2), AM 2 (CLR/RAMP3) and CGRP (CLR/RAMP1) receptors, respectively.

  • GC79280 structure
    GC79280Talogreptide vizaxetan
    CAS: 1186600-65-6
    Purity: >98.00%

    RM2 is a GRPr antagonist.

  • GC79281 structure
    GC79281Adrenotensin (human) TFA
    Purity: >99.00%

    Adrenotensin (human) (Pro-ADM-153-185 (human)) TFA is a 153-185 fragment of precursor peptide of Adrenomedullin.

  • GC79282 structure
    GC79282CTR/AMYR modulator-1
    CAS: 3097482-67-9
    Purity: >99.50%

    CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator.

  • GC81401 structure
    GC81401DD04107
    CAS: 1202877-06-2
    Purity: >99.50%

    DD04107 is a neuronal exocytosis inhibitor with a rat Syt1-C2B domain binding K d of 2.4 μM.