Nicotinic Receptor
Nicotinic acetylcholine receptors is a family of ligand-gated ion channels that plays a significant role in the synaptic signaling and involved in neurological diseases, such as Alzheimer’s, Parkinson’s and schizophrenia etc.
Products Related to Nicotinic Receptor(62)
- GC12959SIB 1553A hydrochlorideCAS: 191611-89-9Purity: >99.00%
SIB 1553A hydrochloride is an orally bioavailable nicotinic acetylcholine receptors (nAChRs) agonist, with selectivity for β4 subunit-containing nAChRs.
- GC13118Dihydro-β-erythroidine hydrobromideCAS: 29734-68-7Purity: >99.50%
Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs.
- GC13644α-Conotoxin EICAS: 170663-33-9Purity: >98%
Selective antagonist of neuromuscular nicotinic receptors α1β1γδ
- GC13678Methyllycaconitine citrateCAS: 112825-05-5; 351344-10-0Purity: >98.00%
Methyllycaconitine citrate is a selective α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist (IC 50 =2nM).
- GC142255-Iodo-A-85380, 5-trimethylstannyl N-BOC derivativeCAS: 213766-21-3Purity: >98%
Precursor to ligand for the α4β2 nicotinic receptor
- GC14296α-Conotoxin PIACAS: 669050-68-4Purity: >98%
Selective antagonist of α6-containing nicotinic receptors
- GC14342Sazetidine A dihydrochlorideCAS: 1197329-42-2Purity: >98%
α4β2 nicotinic acetylcholine receptor ligand
- GC15146PHA 543613 hydrochlorideCAS: 478149-53-0Purity: >98%
PHA 543613 hydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a Ki of 8.8 nM.
- GC15160TC 2559 difumarateCAS: 212332-35-9Purity: >98%
partial agonist of α4β2 nicotinic acetylcholine receptor
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC12959 | SIB 1553A hydrochloride | 191611-89-9 | >99.00% | |
SIB 1553A hydrochloride is an orally bioavailable nicotinic acetylcholine receptors (nAChRs) agonist, with selectivity for β4 subunit-containing nAChRs. | ||||
| GC13052 | SR 16584 | 1150153-86-8 | >98% | |
α3β4 nAChR antagonist | ||||
| GC13064 | NS 1738 | 501684-93-1 | >98.00% | |
positive allosteric modulator of α7 nicotinic acetylcholine receptor | ||||
| GC13118 | Dihydro-β-erythroidine hydrobromide | 29734-68-7 | >99.50% | |
Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. | ||||
| GC13346 | TQS | 353483-92-8 | >99.00% | |
positive allosteric modulator of α7 nACh receptors | ||||
| GC13366 | MG 624 | 77257-42-2 | >98% | |
neuronal α7 nAChR antagonist | ||||
| GC13644 | α-Conotoxin EI | 170663-33-9 | >98% | |
Selective antagonist of neuromuscular nicotinic receptors α1β1γδ | ||||
| GC13678 | Methyllycaconitine citrate | 112825-05-5; 351344-10-0 | >98.00% | |
Methyllycaconitine citrate is a selective α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist (IC 50 =2nM). | ||||
| GC14157 | (-)-Lobeline hydrochloride | 134-63-4 | >99.50% | |
nicotinic receptor partial agonist | ||||
| GC14225 | 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative | 213766-21-3 | >98% | |
Precursor to ligand for the α4β2 nicotinic receptor | ||||
| GC14296 | α-Conotoxin PIA | 669050-68-4 | >98% | |
Selective antagonist of α6-containing nicotinic receptors | ||||
| GC14342 | Sazetidine A dihydrochloride | 1197329-42-2 | >98% | |
α4β2 nicotinic acetylcholine receptor ligand | ||||
| GC14353 | α-Conotoxin ImI | 156467-85-5 | >98% | |
Nicotinic receptor antagonist | ||||
| GC14410 | (±)-Epibatidine | 148152-66-3 | >98% | |
nicotinic agonist | ||||
| GC14588 | Myosmine | 532-12-7 | >99.50% | |
agonist at neuronal nicotinic acetylcholine receptors | ||||
| GC15132 | TC 1698 dihydrochloride | 700834-58-8 | >98% | |
nicotinic α7 receptor agonist | ||||
| GC15141 | ACV 1 | 740980-24-9 | >98% | |
Neuronal nicotinic receptor antagonist | ||||
| GC15146 | PHA 543613 hydrochloride | 478149-53-0 | >98% | |
PHA 543613 hydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a Ki of 8.8 nM. | ||||
| GC15160 | TC 2559 difumarate | 212332-35-9 | >98% | |
partial agonist of α4β2 nicotinic acetylcholine receptor | ||||
| GC15333 | A 844606 | 861119-08-6 | >98% | |
α7 nAChR partial agonist | ||||
| GC15383 | 4-Acetyl-1,1-dimethylpiperazinium iodide | 75667-84-4 | >98% | |
nicotinic agonist | ||||
| GC15703 | Chlorisondamine diiodide | 96750-66-2 | >98% | |
long lasting nicotinic antagonist | ||||
| GC15910 | S 24795 | 304679-75-2 | >98% | |
Partial agonist of α7 nAChR | ||||
| GC15941 | EVP-6124 | 550999-75-2 | >98% | |
A partial agonist of α7 subunit-containing nAChRs | ||||