GLPBio

Somatostatin Receptor

Somatostatin receptor is a G protein-coupled receptor that includes five known somatostatin receptors.

Products Related to Somatostatin Receptor(43)

  • GC62381 structure
    GC62381BIM-23190 hydrochloride
    Purity: >98.50%

    BIM-23190 hydrochloride, a somatostatin analog, a selective SSRT2 and SSRT5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly.

  • GC62843 structure
    GC62843Angiopeptin TFA
    CAS: 2478421-60-0
    Purity: >99.00%

    Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26?nM and 6.92?nM, respectively.

  • GC63137 structure
    GC63137Paltusotine
    CAS: 2172870-89-0
    Purity: >98.50%

    Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist.

  • GC64259 structure
    GC64259SSTR5 antagonist 2 hydrochloride
    CAS: 2988224-31-1
    Purity: >99.00%

    SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM).

  • GC64635 structure
    GC64635AGI-43192
    CAS: 2377491-54-6
    Purity: >99.00%

    AGI-43192 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A).

  • GC64665 structure
    GC64665AGI-41998
    CAS: 2377492-26-5
    Purity: >99.00%

    AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A).

  • GC65313 structure
    GC65313SSTR5 antagonist 1
    CAS: 1628741-91-2
    Purity: >99.00%

    SSTR5 antagonist 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively.

  • GC69003 structure
    GC69003DOTA-LM3 TFA
    Purity: >99.00%

    DOTA-LM3 TFA is a growth hormone receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2, which is also a somatostatin antagonist. DOTA-LM3 TFA is commonly used as an isotopic label for in vivo tumor tracking, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA has good biological distribution, high tumor uptake, good tumor retention and fewer safety issues. 177Lu-DOTA-LM3 TFA can be used for the study of DOTATOC-negative liver metastases, such as pancreatic NETs and extensive tumor thrombosis.

  • GC72086 structure
    GC72086Veldoreotide TFA
    CAS: 2126831-23-8
    Purity: >98.00%

    Veldoreotide (DG3173) TFA a somatostatin analogue, binds to and activate the somatostatin receptors (SSTR) 2, 4, and 5.

  • GC72197 structure
    GC72197Cortistatin 29
    Purity: >99.00%

    Cortistatin 29 is a neuropeptide.

  • GC74368 structure
    GC74368[Nle8] Somatostatin (1-28) (TFA)
    Purity: >99.00%

    [Nle8] Somatostatin (1-28) TFA is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8.

  • GC74393 structure
    GC74393DOTA-LM3
    CAS: 1192362-32-5
    Purity: >98.00%

    DOTA-LM3 is a somatostatin receptor (SSTR) antagonist.

  • GC74394 structure
    GC74394DOTA-JR11
    CAS: 1039726-31-2
    Purity: >98.00%

    DOTA-JR11 is a somatostatin receptor 2 （SSTR2）antagonist.

  • GC74405 structure
    GC74405NODAGA-LM3
    Purity: >99.00%

    NODAGA-LM3 can be labeled by 68Ga for PET imaging.

  • GC79316 structure
    GC79316L-797591 hydrochloride
    CAS: 3026641-74-4
    Purity: >99.50%

    L-797591 hydrochloride is a selective sst 1 agonist.

  • GC79317 structure
    GC79317SSTR3 Agonist-1
    CAS: 3086695-73-7
    Purity: >98.00%

    SSTR3 Agonist-1 (Compound EX 38) is an orally active SSTR3 agonist, with an EC 50 of 0.14 nM.

  • GC79318 structure
    GC79318NOTA-TATE
    CAS: 709043-21-0
    Purity: >98.50%

    NOTA-TATE is a somatostatin receptor 2 ( SSTR2 ) binder.

  • GC79504 structure
    GC79504(R)-Verapamil
    CAS: 38321-02-7
    Purity: >98.50%

    (R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil.

  • GC10729 structure
    GC10729Pasireotide
    CAS: 396091-73-9
    Purity: >98%

    stable cyclohexapeptide somatostatin mimic