Apoptosis

Cyclopentenylcytosine (CPC) is a nucleoside analog that reduces the levels of cytidine triphosphate (CTP) and deoxycytidine triphosphate (dCTP) in leukemic cells by inhibiting CTP synthetase.

Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii.

BAI1 drochloride is a selective apoptosis factor BAX allosteric inhibitors.

KX2-361 (KX-02) is a Src-kinase and tubulin polymerization inhibitor.

NSC260594 induces Apoptosis.

Belapectin (GR-MD-02) is a Galectin-3 (Gal-3) inhibitor.

Avenanthramide A is a ptoalexin, which can be found in oats (Avena sativa L.

Erasin is a potent Erlotinib -resistance antagonizing STAT3 inhibitor with IC50s of 9.7 and 24 μM against STAT3 and STAT1, respectively.

PZ703b drochloride is a Bcl-xl PROTAC degrader that induces apoptosis and inhibits cancer cell proliferation.

AZA197 is a selective small molecule inhibitor of Cdc42.

justicidin A is a nature product that could be isolated form Justicia procumbens.

UCD38B drochloride is a cell permeant, competitive enzymatic uPA inhibitor with an IC50 value of 7 μM.

Oblimersen sodium is a BCL-2 inhibitor targeting BCL-2 RNA.

DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis.

(R)-MRT199665 is an isomer of MRT199665.

PD173952 is a tyrosine kinases inhibitor with IC50s of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk, respectively.

DB818 is a potent inhibitor of Homeobox A9 (HOXA9).

DB818 didrochloride is the didrochloride salt form of DB818.

LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells.

MMRi64 disrupts Mdm2-MdmX interactions.

INCB3619 is a selective and orally active ADAM inhibitor with IC50 of 22 nM and 14 nM for ADAM10 and ADAM17, respectively.

Z-LEVD-FMK is a cell-permeable caspase-4 inhibitor.

RAPTA-C (Ru(η6-p-cymene)Cl2(pta)) acts as an anti-cancer and anti-angiogenic agent.

Ganglioside GD3 diammonium is an acidic glycosphingolipid.