GSK-3
GSK3 (glycogen synthase kinase-3) is a serine/threonine protein kinase which contributes to cell survival, diabetes, insulin resistance and Alzheimer's diseases.
Products Related to GSK-3(59)
- GC69196GSK3 Substrate, α, β subunitPurity: >98%
GSK3 Substrate, α, β subunit is a peptide substrate of glycogen synthase kinase-3 (GSK-3) that can be used to measure GSK-3 activity.
- GC707086-Me-ATP trisodiumPurity: >99.00%
6-Me-ATP (N6-Methyl-ATP) trisodium is a N6-modified ATP derivative.
- GC72931HTH-01-091 TFAPurity: >98.00%
HTH-01-091 TFA is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC50 of 10.5 nM.
- GC73063Tagtociclib hydrateCAS: 2733575-91-0Purity: >99.00%
PF-07104091 drate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively.
- GC73183CDK8-IN-12CAS: 2613307-67-6Purity: >99.00%
CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM.
- GC74261(R)-(+)-O-DemethylbuchenavianineCAS: 1364123-68-1Purity: >98.00%
(R)-(+)-O-Demetlbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK).
- GC79759SkQR1 hydroxideCAS: 1333381-77-3Purity: >98%
SkQR1 hydroxide is a mitochondrial targeted antioxidant.
- GC80873Tovophyllin ACAS: 40738-44-1Purity: >98%
Tovophyllin A is an orally active xanthonoid compound.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC69196 | GSK3 Substrate, α, β subunit | - | >98% | |
GSK3 Substrate, α, β subunit is a peptide substrate of glycogen synthase kinase-3 (GSK-3) that can be used to measure GSK-3 activity. | ||||
| GC70708 | 6-Me-ATP trisodium | - | >99.00% | |
6-Me-ATP (N6-Methyl-ATP) trisodium is a N6-modified ATP derivative. | ||||
| GC72931 | HTH-01-091 TFA | - | >98.00% | |
HTH-01-091 TFA is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC50 of 10.5 nM. | ||||
| GC73063 | Tagtociclib hydrate | 2733575-91-0 | >99.00% | |
PF-07104091 drate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. | ||||
| GC73183 | CDK8-IN-12 | 2613307-67-6 | >99.00% | |
CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM. | ||||
| GC74261 | (R)-(+)-O-Demethylbuchenavianine | 1364123-68-1 | >98.00% | |
(R)-(+)-O-Demetlbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). | ||||
| GC79117 | 8012–3246 | 421586-94-9 | >99.50% | |
8012-3246 is a selective PLK2 inhibitor with an IC 50 of 774.5 nM. | ||||
| GC79759 | SkQR1 hydroxide | 1333381-77-3 | >98% | |
SkQR1 hydroxide is a mitochondrial targeted antioxidant. | ||||
| GC80870 | XL-418 | 871343-09-8 | >95.00% | |
XL-418 is an orally active dual Akt and p70S6K inhibitor with IC 50 s of 1 nM for Akt1 and 2 nM for p70S6K. | ||||
| GC80873 | Tovophyllin A | 40738-44-1 | >98% | |
Tovophyllin A is an orally active xanthonoid compound. | ||||
| GC80874 | ARN25699 | - | >98% | |
ARN25699 is a kinase inhibitor with an IC 50 of 5.5 nM against GSK-3β, 2.2 nM against FYN-α, and 242.3 nM against DYRK1A, and it exhibits oral bioavailability. | ||||
