GLPBio

GSK-3

GSK3 (glycogen synthase kinase-3) is a serine/threonine protein kinase which contributes to cell survival, diabetes, insulin resistance and Alzheimer's diseases.

Products Related to GSK-3(59)

  • GC69196 structure
    GC69196GSK3 Substrate, α, β subunit
    Purity: >98%

    GSK3 Substrate, α, β subunit is a peptide substrate of glycogen synthase kinase-3 (GSK-3) that can be used to measure GSK-3 activity.

  • GC70708 structure
    GC707086-Me-ATP trisodium
    Purity: >99.00%

    6-Me-ATP (N6-Methyl-ATP) trisodium is a N6-modified ATP derivative.

  • GC72931 structure
    GC72931HTH-01-091 TFA
    Purity: >98.00%

    HTH-01-091 TFA is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC50 of 10.5 nM.

  • GC73063 structure
    GC73063Tagtociclib hydrate
    CAS: 2733575-91-0
    Purity: >99.00%

    PF-07104091 drate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively.

  • GC73183 structure
    GC73183CDK8-IN-12
    CAS: 2613307-67-6
    Purity: >99.00%

    CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM.

  • GC74261 structure
    GC74261(R)-(+)-O-Demethylbuchenavianine
    CAS: 1364123-68-1
    Purity: >98.00%

    (R)-(+)-O-Demetlbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK).

  • GC79117 structure
    GC791178012–3246
    CAS: 421586-94-9
    Purity: >99.50%

    8012-3246 is a selective PLK2 inhibitor with an IC 50 of 774.5 nM.

  • GC79759 structure
    GC79759SkQR1 hydroxide
    CAS: 1333381-77-3
    Purity: >98%

    SkQR1 hydroxide is a mitochondrial targeted antioxidant.

  • GC80870 structure
    GC80870XL-418
    CAS: 871343-09-8
    Purity: >95.00%

    XL-418 is an orally active dual Akt and p70S6K inhibitor with IC 50 s of 1 nM for Akt1 and 2 nM for p70S6K.

  • GC80873 structure
    GC80873Tovophyllin A
    CAS: 40738-44-1
    Purity: >98%

    Tovophyllin A is an orally active xanthonoid compound.

  • GC80874 structure
    GC80874ARN25699
    Purity: >98%

    ARN25699 is a kinase inhibitor with an IC 50 of 5.5 nM against GSK-3β, 2.2 nM against FYN-α, and 242.3 nM against DYRK1A, and it exhibits oral bioavailability.