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(S)-DSM1465

Catalog No.GC79592 Copy One-Click Copy Product Info

(S)-DSM1465 is a Plasmodium dihydroorotate dehydrogenase ( DHODH ) inhibitor.

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(S)-DSM1465 Chemical Structure

Cas No.: 3109381-05-4

Size Price Stock Qty
1mg
$288.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of (S)-DSM1465

(S)-DSM1465 is a Plasmodium dihydroorotate dehydrogenase ( DHODH ) inhibitor. (S)-DSM1465 exhibits potential inhibitory activity against Plasmodium falciparum and Plasmodium vivax, and can be used in malaria research [1].

References:
[1]. Roger Victor Bonnert, et al. 2,6-dihydro-7h-pyrazolo[3,4-c]pyridin-7-one derivatives as anti-malarial agents. WO2025247949A1. 2025-05-28.

Chemical Properties of (S)-DSM1465

Cas No. 3109381-05-4 SDF
Formula C17H12ClF6N5O2 M.Wt 467.75
Solubility DMSO: 100 mg/mL (213.79 mM; Need ultrasonic) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (S)-DSM1465

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1 mg 5 mg 10 mg
1 mM 2.1379 mL 10.6895 mL 21.3789 mL
5 mM 427.6 μL 2.1379 mL 4.2758 mL
10 mM 213.8 μL 1.0689 mL 2.1379 mL
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In vivo Formulation Calculator (Clear solution) of (S)-DSM1465

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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