S1P receptor

S1P (sphinogosine-1-phosphate) receptor is a G-protein coupled receptor that involved in regulation of cells proliferation, survival, motility and adhesion etc.

Products Related to S1P receptor(8)

GC14807 Fingolimod (FTY720) HCl
CAS: 162359-56-0
Purity: >99.00%
Fingolimod (FTY720), an immunosuppressant agent, usually used in the treatment of multiple sclerosis, also has anticancer actions and can act as an HDACi (Histone deacetylase inhibitors)[1].
GC16701 SKI II
CAS: 312636-16-1
Purity: >98.00%
Sphingosine kinase(SK) inhibitor
GC11917 PF-543
CAS: 1415562-82-1
Purity: >98.00%
PF-543 is a potent, selective, reversible, and sphingosine-competitive inhibitor of SphK1 with an IC 50 value of 2nM and a Ki value of 3.6 nM.
GC14360 Ozanimod (RPC1063)
CAS: 1306760-87-1
Purity: >99.50%
Ozanimod (RPC1063) is a sphingosine-1-phosphate (S1P) receptor modulator that can cross the blood-brain barrier. Ozanimod selectively binds to S1P1 (EC 50 =1.03nM) and S1P5 (EC 50 =8.6nM) receptors.
GC16660 Ponesimod
CAS: 854107-55-4
Purity: >98.00%
sphingosine-1-phosphate receptor 1 (S1P1) modulator
GC42664 A-971432
CAS: 1240308-45-5
Purity: >98.00%
A-971432 is a sphingosine-1-phosphate receptor 5 (S1P5) agonist that is selective for S1P5 over S1P1 and S1P3 (IC50s = 0.006, 0.362, and >10 μM, respectively).
GC50275 Ex 26
CAS: 1233332-37-0
Purity: >98%
Potent and selective S1P1 receptor antagonist
GC17201 BAF312 (Siponimod)
CAS: 1230487-00-9
Purity: >99.00%
BAF312 (Siponimod) is a selective and orally active sphingosine-1-phosphate (S1P) receptor agonist, with the EC 50 values of 0.39, 750, and 0.98nM for S1P1, S1P4, and S1P5 receptors, respectively.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC14807	Fingolimod (FTY720) HCl	162359-56-0	>99.00%
GC14807	Fingolimod (FTY720), an immunosuppressant agent, usually used in the treatment of multiple sclerosis, also has anticancer actions and can act as an HDACi (Histone deacetylase inhibitors)[1].
GC16701	SKI II	312636-16-1	>98.00%
GC16701	Sphingosine kinase(SK) inhibitor
GC11917	PF-543	1415562-82-1	>98.00%
GC11917	PF-543 is a potent, selective, reversible, and sphingosine-competitive inhibitor of SphK1 with an IC 50 value of 2nM and a Ki value of 3.6 nM.
GC14360	Ozanimod (RPC1063)	1306760-87-1	>99.50%
GC14360	Ozanimod (RPC1063) is a sphingosine-1-phosphate (S1P) receptor modulator that can cross the blood-brain barrier. Ozanimod selectively binds to S1P1 (EC 50 =1.03nM) and S1P5 (EC 50 =8.6nM) receptors.
GC16660	Ponesimod	854107-55-4	>98.00%
GC16660	sphingosine-1-phosphate receptor 1 (S1P1) modulator
GC42664	A-971432	1240308-45-5	>98.00%
GC42664	A-971432 is a sphingosine-1-phosphate receptor 5 (S1P5) agonist that is selective for S1P5 over S1P1 and S1P3 (IC50s = 0.006, 0.362, and >10 μM, respectively).
GC50275	Ex 26	1233332-37-0	>98%
GC50275	Potent and selective S1P1 receptor antagonist
GC17201	BAF312 (Siponimod)	1230487-00-9	>99.00%
GC17201	BAF312 (Siponimod) is a selective and orally active sphingosine-1-phosphate (S1P) receptor agonist, with the EC 50 values of 0.39, 750, and 0.98nM for S1P1, S1P4, and S1P5 receptors, respectively.