GLPBio

Sigvotatug

Catalog No.: GC84560Purity:>99.50%Synonyms: SGN-B6A antibody
Sigvotatug (SGN-B6A antibody) is a human IgG1 κ monoclonal antibody against ITGB6.

Products are for research use only. Not for human use. We do not sell to patients.


Sigvotatug
Cas No.: 2764774-90-3
1mgIn Stock
$270.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Sigvotatug (SGN-B6A antibody) is a human IgG1 κ monoclonal antibody against ITGB6. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control. Sigvotatug can be used as an ADC antibody to synthesize ADC Sigvotatug vedotin [1].

In Vitro, Sigvotatug vedotin (SGN-B6A) is an ADC molecule with anti-tumor activity[1].

References:
[1]. Lyon RP, et al. SGN-B6A: A New Vedotin Antibody-Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications. Mol Cancer Ther. 2023 Dec 1;22(12):1444-1453.

Product Documents

Purity:>99.50%Appearance:A liquid

Chemical Properties

CAS No.
2764774-90-3
Synonyms
SGN-B6A antibody
Molecular Weight
144.48
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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