GLPBio

Sob-AM2

Catalog No.: GC74079
COASDSData Sheet
Sob-AM2 is a potent substrate targeting fatty acid amide drolase (FAAH) expressed in the brain (Km=1.3 μM).

Products are for research use only. Not for human use. We do not sell to patients.

Sob-AM2
Cas No.: 2128258-47-7
1 mgIn Stock
$38.00
1
5 mgIn Stock
$83.00
1
10mgIn Stock
$146.00
1
25mgIn Stock
$351.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Sob-AM2 is a potent substrate targeting fatty acid amide drolase (FAAH) expressed in the brain (Km=1.3 μM), delivering high concentrations of Sobetirome to the central nervous system with minimal peripheral systemic dose, thereby stimulating central troid hormone receptor β (TRβ).

References:
[1]. Meinig J M, et al. Targeting fatty-acid amide drolase with prodrugs for CNS-selective therapy[J]. ACS chemical neuroscience, 2017, 8(11): 2468-2476.

Product Documents

Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
2128258-47-7
Molecular Formula
C21H27NO3
Molecular Weight
341.44
Solubility
DMSO : 20 mg/mL (58.58 mM; Need ultrasonic and warming)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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