SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM. SP 600125, negative control is a methylated analog of SP 600125 that has much lower affinity for JNK isoforms (IC50s = 18 and 24 µM for JNK2 and JNK3, respectively).
SP 600125, negative control
Catalog No.: GC44919Purity:>99.50%Synonyms: JNK Inhibitor II, negative control
SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 54642-23-8
1mgIn Stock
$143.00
1
5mgIn Stock
$40.00
1
10mgIn Stock
$63.00
1
25mgIn Stock
$127.00
1
50mgIn Stock
$194.00
1
100mgIn Stock
$288.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $143.00 | In Stock | 1 | |
| 5mg | $40.00 | In Stock | 1 | |
| 10mg | $63.00 | In Stock | 1 | |
| 25mg | $127.00 | In Stock | 1 | |
| 50mg | $194.00 | In Stock | 1 | |
| 100mg | $288.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.50%Appearance:A solid
Chemical Properties
CAS No.
54642-23-8
Synonyms
JNK Inhibitor II, negative control
SMILES
CN1N=C2C3=C(C=CC=C31)C(C4=CC=CC=C42)=O
Molecular Formula
C15H10N2O
Molecular Weight
234.3
Solubility
DMSO: 10 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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