Acetaminophen glucuronide potassium (APAP-glu potassium) is the inactive glucuronide metabolite of Acetaminophen. Acetaminophen glucuronide potassium can be used as a biomarker to measure glucuronidation activity or hepatic drug metabolism capacity [1].
References:
[1]. Court MH, et al. The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure. J Pharmacol Exp Ther. 2013 May;345(2):297-307.
[2]. Morris ME, et al. Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans. J Pharm Sci. 1984 Aug;73(8):1038-41.
References:
[1]. Court MH, et al. The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure. J Pharmacol Exp Ther. 2013 May;345(2):297-307.
[2]. Morris ME, et al. Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans. J Pharm Sci. 1984 Aug;73(8):1038-41.