Anti-Mouse PD-1 Antibody (RMP1-14), CY7 labeled, is an Anti-Mouse PD-1 Antibody (RMP1-14) derivative carrying dye CY7. Anti-Mouse PD-1 Antibody (RMP1-14) is an anti-mouse PD-1 IgG2a antibody. Anti-Mouse PD-1 Antibody (RMP1-14) can be used for the study of colon carcinoma [1].
In Vivo, Animal Model: Mouse CT26.CL25 liver metastasis model[1] Dosage: 10 mg/kg Administration: ip, every 3 days for 3-4 doses Result: Failed to significantly change immune cells when used alone. Increased the M1/M2 ratio, increased the number of mature CD4+ T cells and CD8+ T cells, increased the expression of IFN-γ and TNF-α when used with the combination of CAPOX. Animal Model: C57BL/6J mouse models[2] Dosage: 50-200 μg/mouse Administration: intradermal injection, single dose Result: Increased the number of spontaneous scratching in mice.
In Vitro, Anti-Mouse PD-1 Antibody (RMP1-14), CY7 labeled, is an Anti-Mouse PD-1 Antibody (RMP1-14) derivative carrying dye CY7.
In Vivo, Animal Model: Mouse CT26.CL25 liver metastasis model[1] Dosage: 10 mg/kg Administration: ip, every 3 days for 3-4 doses Result: Failed to significantly change immune cells when used alone. Increased the M1/M2 ratio, increased the number of mature CD4+ T cells and CD8+ T cells, increased the expression of IFN-γ and TNF-α when used with the combination of CAPOX. Animal Model: C57BL/6J mouse models[2] Dosage: 50-200 μg/mouse Administration: intradermal injection, single dose Result: Increased the number of spontaneous scratching in mice.
In Vitro, Anti-Mouse PD-1 Antibody (RMP1-14), CY7 labeled, is an Anti-Mouse PD-1 Antibody (RMP1-14) derivative carrying dye CY7.