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Bacoside A3 (Synonyms: Bacopa Pgp)

Catalog No.GC18312 Copy One-Click Copy Product Info

Bacoside A3, una saponina triterpenoide, es uno de los principales componentes activos de Bacopa monnieri.

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Bacoside A3 Chemical Structure

Cas No.: 157408-08-7

Tamaño Precio Disponibilidad Cantidad
1mg
97,00 $
Disponible
5mg
243,00 $
Disponible
10mg
377,00 $
Disponible

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Bacoside A3

Bacoside A3 is a triterpenoid saponin first isolated from B. monniera. Bacoside A3 inhibits the ATP-binding cassette transporter P-glycoprotein (P-gp), decreasing efflux 4-fold compared with control in vitro. An extract containing bacoside A3 and bacopaside II (4 and 1.3 ug/mg extract, respectively) administered for eight days at a dose of 10-30 mg/kg reduces opioid withdrawal-induced depression in mice using the forced swim test. Bacoside A3 also has antioxidant properties following liver and kidney damage induced by street heroin in rats.

Chemical Properties of Bacoside A3

Cas No. 157408-08-7 SDF
Sinónimos Bacopa Pgp
Chemical Name N/A
Canonical SMILES CC1(O)CC(/C=C(C)/C)OC2(OC3)CC43C5(C)CCC6C(C)(C)C(OC7OC(CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C7OC9OC(CO)C(O)C9O)CCC6(C)C5CCC4C21
Formula C47H76O18 M.Wt 929.1
Solubility DMSO : 100 mg/mL (107.63 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Bacoside A3

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.0763 mL 5.3816 mL 10.7631 mL
5 mM 215.3 μL 1.0763 mL 2.1526 mL
10 mM 107.6 μL 538.2 μL 1.0763 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Bacoside A3

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Bacoside A3

Average Rating: 5 ★★★★★ (Based on Reviews and 33 reference(s) in Google Scholar.)

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