Bis-PEG6-acid |
| Catalog No.GC60088 |
Bis-PEG6-acid es un conector PROTAC basado en PEG que se puede utilizar en la sÍntesis de PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 119189-70-7
Sample solution is provided at 25 µL, 10mM.
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Bis-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Zorba A, et al. Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7285-E7292.
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