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DSPE-PEG2000-CTP

Catalog No.GC79702 Copy One-Click Copy Product Info

DSPE-PEG2000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP.

Products are for research use only. Not for human use. We do not sell to patients.

DSPE-PEG2000-CTP Chemical Structure

Tamaño Precio Disponibilidad Cantidad
5mg
346,00 $
Disponible

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of DSPE-PEG2000-CTP

DSPE-PEG2000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP. CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG2000-CTP can be used for drug delivery [1].

In Vitro, Lipids used to prepare nanoparticles are a class of amphiphilic biomolecules that combine structural diversity, biocompatibility, and functional tunability. As the core framework of nanodelivery systems, they not only form lipid bilayers or solid matrices through self-assembly to encapsulate lipophilic or hydrophilic drugs, but can also be further subdivided according to formulation requirements into structural lipids (such as phospholipids and triglycerides), functional lipids (such as ionizable cationic lipids used for nucleic acid condensation and endosome escape), and sterically stable lipids (such as PEGylated lipids).

References:
[1]. Gallicano, G. I., et al., (2022). Reversing Cardiac Hypertrophy at the Source Using a Cardiac Targeting Peptide Linked to miRNA106a: Targeting Genes That Cause Cardiac Hypertrophy.

Chemical Properties of DSPE-PEG2000-CTP

Cas No. SDF
Formula M.Wt
Solubility Storage Store at -80°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of DSPE-PEG2000-CTP

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for DSPE-PEG2000-CTP

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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