Masupirdine mesylate (Synonyms: SUVN-502 mesylate) |
| Catalog No.GC38509 |
El mesilato de masupirdina (mesilato SUVN-502) es un antagonista del receptor 5-HT6 potente, selectivo, biodisponible por vÍa oral y penetrante en el cerebro (Ki de 2,04 nM para el receptor 5-HT6 humano).
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Cas No.: 1791396-46-7
Sample solution is provided at 25 µL, 10mM.
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Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease[1].
[1]. Nirogi R, et al. Discovery and Development of 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer's Disease. J Med Chem. 2017 Mar 9;60(5):1843-1859.
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