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HPI 1

Catalog No.GC11045

HPI 1 es un potente antagonista de GLI con un valor IC50 de 1,1 μM. HPI 1 muestra actividad antiproliferativa. HPI 1 disminuye la expresiÓn de ARNm de GLI1. HPI 1 inhibe la formaciÓn de colonias de manera dependiente de la dosis.

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HPI 1 Chemical Structure

Cas No.: 599150-20-6

Tamaño Precio Disponibilidad Cantidad
5mg
114,00 $
Disponible
10mg
204,00 $
Disponible
25mg
479,00 $
Disponible
50mg
845,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
Hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4 and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation). Also inhibits Hh pathway activation

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Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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