Ipronidazole-d3 is intended for use as an internal standard for the quantification of ipronidazole by GC- or LC-MS. Ipronidazole is a nitroimidazole antiprotozoal agent.1 Dietary administration of ipronidazole (0.00312-0.0094% w/w) reduces H. meleagridis-induced mortality in young turkeys. It also induces 100% disease clearance in bulls infected with T. foetus when administered at a dose of 60 g/animal.2 Formulations containing ipronidazole have been used in the treatment of veterinary histomoniasis in turkeys and swine dysentery.
1.Bowen, T.E., Sullivan, T.W., and Grace, O.D.Effect of cupric sulfate on the prophylactic efficacy of 2-acetylamino-5-nitrothiazole, nifursol and ipronidazole against histomoniasis in turkeysPoult. Sci.50(6)1668-1672(1971) 2.Skirrow, S.Z., and Bondurant, R.H.Treatment of bovine trichomoniasis with ipronidazoleAust. Vet. J.65(5)156(1988)