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| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $1,316.00 | In Stock | 1 | |
| 1mg | $459.00 | In Stock | 1 | |
| 5mg | $873.00 | In Stock | 1 | |
| 10mg | $1,471.00 | In Stock | 1 | |
| 50mg | $4,597.00 | In Stock | 1 |
MSI-1701 is an analogue of MSI-1436 which can control weight gain and blood glucose level extracted from patent US 7410959 B1.
Analogues that differ from MSI-1436 at only a single stereocenter, such as MSI-1701 (the polyamine at C-3) or MSI-1777 (the methyl at C-20) exhibit significantly reduced activity, while MSI-1673 (the OH at C-7) is completely inactive[1].
[1]. Michael Zasloff, et al. Therapeutic uses for aminosterol compounds. US 7410959 B1.
Animal experiment: | Experiments are performed using age-matched (4 to 5 weeks old) male mice provided food and water ad lib. Mice corresponding to a single experimental cohort are housed together in a single cage. Animals are used 1 week after arrival. Drug dosing is conducted with 10 mg/kg of each compound (including MSI-1701) via the i.p. route every 3 days for 4 doses, beginning on day 0[1]. |
References: [1]. Michael Zasloff, et al. Therapeutic uses for aminosterol compounds. US 7410959 B1. | |