N-Palmitoyl-l-leucine (GK144) is a secreted phospholipases A 2 inhibitor. N-Palmitoyl-l-leucine can be used for inflammatory diseases [1].
References:
[1]. Mouchlis VD, et al. Inhibition of secreted phospholipases A₂ by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations. Bioorg Med Chem. 2011 Jan 15;19(2):735-43.
References:
[1]. Mouchlis VD, et al. Inhibition of secreted phospholipases A₂ by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations. Bioorg Med Chem. 2011 Jan 15;19(2):735-43.