GLPBio

NRX-204647

Catalog No.: GC79767Purity:>98%
NRX-204647 is a potent activator of retinoic acid nuclear (RAR) with higher specificity than that to RAR and RAR.

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.


NRX-204647
Cas No.: 1351452-80-6
1mgIn Stock
$216.00
1

Citas (Citations)

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Descripción (Description)

NRX-204647 is a potent activator of retinoic acid nuclear (RAR) with higher specificity than that to RAR and RAR. NRX-204647 can inhibit bone formation. NRX-204647 significantly reduces bone volume/tissue volume (BV/TV). NRX-204647 can be studied in anti-cancer research [1] [2].

References:
[1]. Uchibe, K., et al., (2017). Genetic and pharmacological inhibition of retinoic acid receptor γ function promotes endochondral bone formation. Journal of orthopaedic research: official publication of the Orthopaedic Research Society, 35(5), 1096-1105.
[2]. Garcia, S. A., et al., (2020). Understanding the Action of RARγ Agonists on Human Osteochondroma Explants. International journal of molecular sciences, 21(8), 2686.

Propiedades químicas (Chemical Properties)

N.º CAS
1351452-80-6
Fórmula molecular
C24H27NO3
Peso molecular
377.48
Almacenamiento
Store at -20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

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